Research on pain sensation, HU Academy of Science

Projekt abgeschlossen

The Project investigates in detail the signalling of endocannabinoids in the spinal cord, with the aim of better understanding their roles in chronic pain and with the potential to find more specific phar-macological interventions with less side effects.
 

Land/Region Thema Periode Budget
Ungarn
Wirtschaftswachstum fördern und Arbeitsbedingungen verbessern
Forschung und Entwicklung
15.10.2010 - 30.04.2016
CHF 985'000

Note: the texts under all the headings, with the exception of 'Results achieved', describe the situation before the start of the project.

Hintergrund 1. Reforms for a knowledge-based economy are at the heart of the EUs reform agenda. While Hungary has a tradition of academic research, the country intends to improve its innovation profile through the further development of key technologies. Among these are technology industries in the fields that are also the focus of the Swiss Contribution Call for Proposals for R&D: life sciences and biotechnology, medical technology, material science and nanotechnology, environmental technology and technology of energy-saving and renewed alternative energy resources. The Swiss Contribution offers an opportunity for Swiss and Hungarian research institutions to cooperate and build partnerships for mutual benefit.
2. Pain is an important health problem, and chronic pain can often not be treated adequately. For this reason there is a need for new pain therapeutics. Recent discoveries indicate that cannabinoid signalling in the brain is far more complex than initially thought and this raises hopes that there are molecular signalling pathways, which may become future drug targets.

Ziele

The project will contribute to novel approaches in pain treatment through the discovery of novel molecular pathways mediating pathological pain.

The purpose of the project is to reveal the precise molecular and anatomical architecture, physiological significance, and pathological importance of endocannabinoid signaling in the regulation of pain.

Zielgruppen

Junior researchers in Hungary, researchers in academia, pharmaceutical research industry, and, in the long run, patients.

Aktivitäten

The project consists of various molecular, anatomical, physiological and behavioural experiments on pain signalling pathways and the development of models to be analysed.

Resultate

Erreichte Resultate:  

  • All intended molecular, anatomical, physiological and behavioural experiments on pain signalling pathways have been successfully completed.
  • The development of models has been analysed
  • The results have been published in scientific papers and presented at international conferences

 


Verantwortliche Direktion/Bundesamt DEZA
Kreditbereich Schweizer Beitrag an die erweiterte EU
Projektpartner Vertragspartner
Ausländische staatliche Institution
  • National State Institute North


Budget Laufende Phase Schweizer Beitrag CHF   985'000 Bereits ausgegebenes Schweizer Budget CHF   903'723
Projektphasen

Phase 1 15.10.2010 - 30.04.2016   (Completed)